• Pharmacology

    Anti-Tubercular drugs

    Anti-Tubercular drugs Tuberculosis is a granulomatous disease and a major health problem in developing countries. About 1/3rd of the world’s population is infected with tuberculosis. The causative organism Mycobacterium tuberculosis. Classification First line drugs It has high anti-tubercular efficacy as well as low toxicity. Example: Isoniazid (H) Rifampicin (R) Pyrazinamide (Z) Ethambutol (E) Streptomycin (S) Second line drugs These drugs have either low anti-tubercular efficacy or higher toxicity or both and are used in special circumstances only. Ethionamide (Eto) Prothionamide (Pto) Cycloserine (Cs) Para amino salicylic acid (PAS) Rifabutin Terizidone Thiacetazone (Thz) Fluoroquinolones Ofloxacin (Ofx) Levofloxacin (Lvx or Lfx) Moxifloxacin (Mfx) Ciprofloxacin (Cfx) Injectable Kanamycin (Km) Amikacin (Am) Capreomycin (Cm)…

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