Pharmacology

General principle of chemotherapy

General principle of chemotherapy Chemotherapy ·         Chemo –  Chemical, Therapy – Treatment ·         The treatment of disease by means of chemicals that have a specific toxic effect upon the disease producing microorganisms or that selectively destroy cancerous tissue. Antibiotics ·         Antibiotics are the substance produce by microorganism, which selectively suppress the growth or kill other …

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Anti-Tubercular drugs

Anti-Tubercular drugs ·         Tuberculosis is a granulomatous disease and a major health problem in developing countries. ·         About 1/3rd of the world’s population is infected with tuberculosis. ·         The causative organism Mycobacterium tuberculosis. Classification A.    First line drugs ·         It has high anti-tubercular efficacy as well as low toxicity. ·         Example: o   Isoniazid (H) o   …

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Immunostimulants

Immunostimulants Immunology The basic causes of disease in human beings is the invasion of pathogenic microorganism (both bacteria and virus). The power of the body to resist the effect of the invasion of microorganisms is called immunity. The lack of such ability to resist infection caused by pathogenic microorganisms is called susceptibility. What affect immune …

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IMMUNOSUPPRESSANT

IMMUNOSUPPRESSANT ·         Immunosuppressant are drugs that inhibit cellular or humoral or both types of immune responses. ·         These drugs have met a high degree of success in organ transplant and autoimmune diseases. Cytokine ·         Cytokines are soluble, antigen-nonspecific signaling proteins that bind to cell surface receptors on a variety of cells. ·         Cytokine includes interleukins …

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Sexually transmitted disease (STD)

Sexually transmitted disease (STD) ·         It is a group of communicable diseases in which sexual contact is the most important mode of transmission. ·         Sexual intercourse ·         Oral-genital contact or in non-sexual ways. ·         IV drug ·         Congenitally transmitted Types 1.      Viral o   ADIS o   Genital herpes simplex o   Genital warts 2.      Bacterial o   Syphilis …

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Malaria & Anti-Malarial Drugs

Malaria ·         A disease caused by a Plasmodium parasite, transmitted by the bite of infected Anopheles mosquito. ·         Malaria caused by following species of parasites 1.      Plasmodium vivax 2.      Plasmodium ovale 3.      Plasmodium falciparum 4.      Plasmodium malariae 5.      Plasmodium knowlesi ·         According to WHO estimation (2011) nearly 0.655 million death occur due to malaria each …

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BRONCHIAL ASTHMA

BRONCHIAL ASTHMA  Asthma is chronic inflammation disease of air way that is characterized by increase responsiveness of tracheobronchial tree to a multiplicity of stimuli. Results: Narrowing of air tubes Increased secretion Mucosal oedema Mucous plugging Dyspnoea (shortness of breath) Wheezing Cough (persistent) STIMULUS ·         Tobacco smoke ·         Infections such as colds, flu, or pneumonia ·         …

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