Dash Smrutiranjan

Hi....!! My name is Smrutiranjan Dash, From Odisha, India. Professionally I am Assistant Professor  at The Pharmaceutical College, Barpali, Odisha, department of Pharmacology.

IMMUNOSUPPRESSANT

IMMUNOSUPPRESSANT ·         Immunosuppressant are drugs that inhibit cellular or humoral or both types of immune responses. ·         These drugs have met a high degree of success in organ transplant and autoimmune diseases. Cytokine ·         Cytokines are soluble, antigen-nonspecific signaling proteins that bind to cell surface receptors on a variety of cells. ·         Cytokine includes interleukins …

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Sexually transmitted disease (STD)

Sexually transmitted disease (STD) ·         It is a group of communicable diseases in which sexual contact is the most important mode of transmission. ·         Sexual intercourse ·         Oral-genital contact or in non-sexual ways. ·         IV drug ·         Congenitally transmitted Types 1.      Viral o   ADIS o   Genital herpes simplex o   Genital warts 2.      Bacterial o   Syphilis …

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Malaria & Anti-Malarial Drugs

Malaria ·         A disease caused by a Plasmodium parasite, transmitted by the bite of infected Anopheles mosquito. ·         Malaria caused by following species of parasites 1.      Plasmodium vivax 2.      Plasmodium ovale 3.      Plasmodium falciparum 4.      Plasmodium malariae 5.      Plasmodium knowlesi ·         According to WHO estimation (2011) nearly 0.655 million death occur due to malaria each …

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BRONCHIAL ASTHMA

BRONCHIAL ASTHMA  Asthma is chronic inflammation disease of air way that is characterized by increase responsiveness of tracheobronchial tree to a multiplicity of stimuli. Results: Narrowing of air tubes Increased secretion Mucosal oedema Mucous plugging Dyspnoea (shortness of breath) Wheezing Cough (persistent) STIMULUS ·         Tobacco smoke ·         Infections such as colds, flu, or pneumonia ·         …

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Drugs used in peptic ulcer

PEPTIC ULCER ·         Peptic ulcer is gastrointestinal disorder which is exposed to gastric acid and pepsin on the lining of the esophagus, stomach and small intestine. ·         There are two type of peptic ulcer 1.       Gastric ulcer (lining of the stomach) 2.       Duodenal ulcer (from in the upper part of the small intestine) PARTS OF …

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Drug & Disease Classification

DRUGS ·         Any substances that, when administered via various form causes a temporary physiological and often psychological changes in the body. OR ·         A chemical substance which when administered in the living organism, produce biological effect. DISEASE ·         A particular abnormal condition that affects the structure or function of organism, and that is not due …

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ICH Guideline For Pharmacovigilance

ICH GUIDELINE FOR PHARMACOVIGILANCE Organization and objective of ICH Expedited reporting Individual case safety reports Periodic safety update reports Post approval expedited reporting Pharmacovigilance planning Good clinical practice in pharmacovigilance studies ORGANIZATION AND OBJECTIVE OF ICH   •       ICH is the international council/conference on harmonization of technical requirement for registration of pharmaceuticals for Human Use. …

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Chemotherapy of Malignancy

CANCER ·         Cancer is the uncontrolled proliferation and abnormal multiplication of cells within the body. ·         A mass of tissue formed as a result of; o   Abnormal o   Excessive o   Uncoordinated o   Autonomous and o   purposeless o   Proliferation of cells THE CELL CYCLE ·         Malignant cells go through normal mitosis but synthesize DNA and divide …

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